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Do these results reflect a past, new and/or chronic EBV infection?

EBV Ab VCA, IgG >600.0 High EBV Early Antigen Ab, IgG 48.1 High

Here's some background on the various Epstein Barr Antigen and Antibody tests that we have in the ODX software:

Epstein-Barr virus (EBV) is a herpes virus that only occurs in humans. Epstein-Barr is the most common cause of infectious mononucleosis. It is estimated that 90% of adults have been infected with EBV. The presence of antibodies to EBV-associated antigens indicates exposure to the virus and may reflect active or past infection.


EBV VCA IgG antibodies indicate a current or past infection These antibodies increase early in an EBV infection, peak at 2-4 weeks post-onset, and then decline but do persist throughout an exposed individual’s lifetime.
The result of >600 is considered elevated and is an indication of a current or past infection. 
A current infection will likely be symptomatic. 
A past infection is very common as a high % of the population has been exposed to EBV at some point in their lives.

EBV Early Antigen Ab, IgG

EBV Early Antigen, IgG antibodies appear during the acute phase of EBV infection and then often become undetectable in 3-6 months, although 20% of exposed individuals may have elevated early antigen IgG levels for years.

The result of 48.1 is elevated and is an indication of a current, acute EBV infection. 


It is hard to say equivocally what's going on but the results of these 2 tests point towards an active infection. However, there is a chance that these titers are elevated in a patient with a past infection.